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Depression
While most people feel sad or blue at some point in their lives, clinical depression is a mood disorder in which persistent feelings of sadness, anger, frustration or "emptiness" interfere with everyday life for an extended time.
Clinical depression is one of the most common mental illnesses, and can cause people to lose pleasure in daily life, complicate other medical conditions, and, if severe enough, lead to suicide.
Symptoms of clinical depression include:
- Persistent sad, anxious or "empty" mood
- Feeling guilty, hopeless or worthless
- Restlessness, irritability
- Difficulty concentrating, remembering or making decisions
- Sleeping too much or too little, nighttime or early morning waking
- Reduced appetite and weight loss, or increased appetite and weight gain
- Loss of pleasure and interest in activities once enjoyed, including sex
- Persistent physical symptoms that do not respond to treatment (such as chronic pain or digestive disorders)
- Fatigue or loss of energy
- Thoughts of suicide or death
The Psychiatry and Behavioral Health Research Center is running a trial for individuals 18-55 years old previously diagnosed with Major Depressive Disorder (MDD) and have begun experiencing depressive symptoms in the last 6 months.
- Patients will be given (randomly) SEP-225289 (an investigational medication), Effexor XR or placebo for 8 weeks.
- Study purpose is to compare the effectiveness of SEP-225289 as compared to placebo in patients' MDD symptoms.
- Patients will meet with a research doctor and staff for 13 visits over 9 weeks.
- Patients will be compensated for each visit with a $50 gift certificate for their time and effort.
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